22 inches deep seems pretty slim to me, considering the original woody was 16 inches at the base and flared to 20 inches at the CP base. I assume you are using an LCD monitor?
Since I am in the midst of my never ending wood grain cab I can give you a couple of tips that I learned:
1) be careful with the glue, and wood filler. Even if its "stainable" it won't stain the same as the rest of your wood. Be careful with that stuff. I built my CP first, and was a little sloppy with it, and there are all these issues I have had to deal with on the finish of it. As a rule, don't get any glue or wood filler on anything you intend on staining and letting other people see.
2) The finish will take forever to do right. It just will. Apply in multiple, thin layers, steel wool in between coats. It takes like 5 hours or so for a coat to dry, you are looking at 2 coats, plust 2 more of poly, that is a solid week of stain, dry, wool, stain, dry, sand...
Mine is 24 inches wide, I didn't want a huge bezel around my monitor, and since my screen is like 17 inches wide, 24 leaves a 3.5 inch bezel on each side, which I think is fine. Not saying that the extra 1.5 inches is a huge difference, but consider, 24 inches is really easy to measure, versus something like 25.5. Its easy to find the middle (only 12 inches, versus 12.75) 24 is a nice easy number to deal with, I would advise moving to 24 inches, or up to 26.
As a general rule, build your cab around your monitor. Having a large bezel makes a cab look bad in my opinion.