That's where I think design comes into play. Those cabs at mameroom look very solid in their design. So the kreg jig particle board route is okay. I guess to clarify I meant that those types of joints on particle board can be weak if used alone. If there are other supporting pieces then it can make for a pretty stong cab depending upon how it's done. Typical DIYers however usually lack structural engineering skills to produce such a design. If you use a more solid material then it isn't so susceptible to the design and would be more forgiving.
I am no woodworking expert by any means, however I have made my own tables, jewelry boxes, cabinets, etc. so I am familiar with a lot of the techniques.
one easy way to make a strong podium would be to make it like the roman numeral 2 looking from above like this " II ". This is simply four pieces of wood and four dado cuts. You could stop the vertical pieces in the middle just short of the top and put a horizontal piece in there. This way you can still add your CP and have the wires all concealed. This would also keep the sides flush all the way to the top. If however you want people to stand on the sides as well, then I think it makes more sense to have the CP overhang over the edge. This basic shape works good for this too. Some things to think about are people's feet. You need a recess down there for their feet to stand comfortably at the podium or the CP needs some serious overhang. Also if the top is going to be angled, think about how this is going to work for people on the sides. That basic double I-beam shape is a pretty stable base support that can be quite adaptable. Typically the sides are fatter at the bottom and narrower at the top to increase stability.
Reason I am thinking 5/8 is because I am planning to laminate. 5/8 + 1/16 + 1/16 = ~3/4 with some glue in there. This works nicely with the 3/4 T-molding. Never thought about just painting a cab. Sounds easy enough and certainly cheaper. You'll get a smoother finish with MDF over particle board, however water resistance is always an issue with these (and really any) pressed materials.