I won't argue about the speed issues Hyperspin has (due to lots of beautiful artwork/video's and such, you might run into some troubles there), but the main reason YOU probrably don't want to use Hyperspin is the set up. You said you wanted something that is easy to use and hard to screw up, well, then HS is NOT what you are looking for.
Setting up HS is something that takes a ton of time (assuming you're going for multiple emulators), involves a LOT of swearing, and has a "you're-gonna-screw-up-at-least-a-couple-times"-guarantee. That's the price you pay for a otherwise perfect FE. It looks awesome, is easy to control once set up, is fully customizable, is compatible with EVERYTHING,...
Even though that might sound bad at first, I don't look at it as a purely bad property. By being obliged to take your time to look into the inner workings of the FE, you learn a lot. After a while you'll know exactly where to find everything, how everything works and where to find everything. This makes things easier when setting up additional emulators, making changes, installing updates, troubleshooting,... The HS team also provides you with a TON of "how-to" guides and tutorials to help you with the complicated setup, all accompanied by tons of screenshots, links and even video's.
If you're really looking for something easy to set up, hard to screw up and easy to use, I would recommend Maximus Arcade. That FE, on the other hand, leaves little space for customization and tweaking. You simply can't have both...
Another general word of advice: look around! There's a whole bunch of FE's out there, all different and made with other priorities in mind, so look around. I'm sure you can quickly make a list of FE's by just scrolling through the forum here and the wiki. Go to the sites of those FE's, look at screenshots, check youtube video's,... Just look at them and see which one you like best. The setting up part might be a pain, but know that you'll get through that and that there's plenty help out here. Going the easy way and having to look at that dull and ugly FE just because you were too lazy to look into "harder" ones on the other hand, we can't help you with.
Hope the above is of any help,
Good luck!