Actually, I think with the newer HyperSpin 1.0, they fixed the scripting for NullDC. You would need to point it to the correct directories (where NullDC and the Roms are located), but otherwise I think it might work easily with the new version.
I checked my settings and it looks like they've been integrated into the default settings for HyperSpin 1.0.
I'd give it a shot and let us know if you have any problems/errors.