I don’t have my computer booting up to MaLa so I don’t know for sure whether or not it works, but I can’t imagine why it wouldn’t.
Let me see if I can remember how I set this up...
What I did is set my video card to dualview (I believe that’s what the nVidia driver calls it) and have the orientation set as one monitor on top of the other. Monitor #1 (the primary) is on top, on monitor #2 (the “marquee” monitor) is on the bottom. Then I create my own layout in MaLa and specify a resolution for the layout that doubles the normal number of vertical pixels. So for instance, instead of 800x600, you would create a layout with an 800x1200 resolution. At that point you can place everything where you’d like it. I use all of the real estate on monitor #2 to display instruction cards, special moves, wallpapers, etc. MAME is set to run on the primary, and your second monitor will keep displaying whatever you have set throughout the game.
I do have to make sure I run MAME at a fixed resolution to match my layout so the layout doesn’t get shifted when I exit a game. (So I have to run all my games at 1024x768 to match the 1024x1536 layout – that may or not be an issue for you in terms of taking a performance hit). I’ll also tell you that with this setup, I used to get random crashes on v1.04 of MaLa. Don’t know if it was a video card issue or a MaLa issue. I haven’t had a lot of game time recently with 1.05 – so far so good, but I’ll have to wait and see how stable it is as I put more play time in. I’m also playing on a different rig now so that might be the difference.
I hope this helps… If not, you can probably run a quick search on this topic. I remember seeing quite a few people running similar setups… two of them being RandyT and NickG.