The officials are a part of the game and, being human, they make mistakes. Just like players and coaches, officials have judgement calls on every play and sometimes make mistakes.
I will say the same thing here that I tell my stepson when he bitches about a call. When the outcome of a game comes down to one call from an official, the players have to look first at what they did before blaming the officials. Sure, the blown call was bad, but if SD had played ANY defense yesterday, they still could have won. Giving up 39 points isnt going to win MANY games at all. Rivers picks didn't help either.
The replay screwup earlier doesn't help at all, but to blame the loss on the refs does the entire team a dis-service. We need to teach personal responsibility instead of how to blame others.