No problem with that. Most of us never worked with wood before building a cab, or at least never doing detailed work like this. With the proper tools: router, circular saw, jigsaw, and drill, you can do it.
Take several measurements and mark out all the cuts on your wood. MDF cuts like butter and is extremely easy to use. It has no grain, just very messy.
If you have time and patience, there is no reason it won't look great. When you start the project, make a thread in the project announcement forum. As you work on it you can get immediate feedback to make your project great.