Thanks for the suggestions so far.  
Circuit Writer pen is out.  
Since what I am doing is basically a bunch of switchs, I am going with a 1 layer design.  (I also didn't want to deal with tracers crossing over each other.)  I am running off of a 12 position switch.  (It took a while to find a strong enough DC switch paired to a relay with a coil that it would work with that would do enough for me.)  
More details to follow.  I am still waiting for my order from allied electronics to show up.  
I built a proof of concept, but now it is time for a 1st generation working prototype.  
I'll be posting more on this one.  But I warn you, it isn't cheap.  I have way too much into it now.  Failure is NOT an option.   

  All because I wanted to play several light gun games without the hassle of switching jamma connectors.