I use it on all my cabinets and I love it.
It supports a huge selection of emulators, I currently run MAME32, DAPHNE, Visual Pinball, Fusion32 (for Genesis, Sega CD, 32X and Sega Master System), Nesticle, SNES9x, Magic Engine, plus I have batch files for Madden 2007 and Tiger Woods 2007 that the front end can launch.
It is a super easy to setup frontend and works well with just about every setup I have thrown at it