besides, the steelers defense is riddled with injuries from sunday alone...their cornerback is most likely out with a high ankle sprain leaving Deion Branch and Bobby Engram to run free....
I could go for the easy pick, but what the heck, its only a game, right? 
I'll give you a perfect example of a tough game to pick:
New York Giants vs. New York Jets
Both teams have the potential to suck, but NYG certainly has better chance to explode with Plaxico Burress (how do you cover a guy who looks 8' tall?) However, that game could absolutely go either way.
There are several teams you would like to pick against, but they're all at home. Arizona at St. Louis is like that.
Another example - Miami at Houston. Common sense says Houston wins this one, but can Miami really lose 5 in a row?
Geez, this week is hard. I'm pretty sure Indy is going to kick the ---steaming pile of meadow muffin--- out of Tampa Bay as a gift to Tony Dungy. That may be the game I pick.