It's a fine idea. I used to do it, and it's fairly quick. Every week or so I'd give the thing a proper reboot. No real reason why, I just felt better about it somehow.
BUT... I can't do it anymore. My KeyWiz loses its memory. :-(
And yes, I'm already trying to come up with a rechargeable battery solution, so it won't lose memory during hibernation (if anyone has thoughts in this area so I don't stumble blindly into it, let me know).
Chemame