I run an overclocked AMD FX9590 computer and plan to illuminate the water cooling reservoir and the inside case which is (or will be) visible from the outside of my rig through a side window.
The AMD FX9590 CPU is 220 watts to begin with so it's a real beotch to cool when it ISN'T overclocked but at 5.1 to 5.2ghz, things go sideways and temps go over real quick. so as of late i've dialled it back a bit closer to stock.
So, having a quick "green yes go, red no stop" illumination will give it some flash... but also a quick visual reference for my system status. I have all kinds of monitoring software running, but I'm not always able to see it, or actively monitor it. if things are going bad, I can see what's up or kill the process before it suicides.