If you pre-drill the holes, you shouldn't have any splitting or cracking. Make sure you drill holes of the proper size; if you pre-drill too big, your screws won't hold. If you clamp the boards in place and use Titebond wood glue, or something similar, you really shouldn't need the screws. They do help speed up the process, though: apply glue to scraps, clamp in position, pre-drill screw holes, insert screws, remove clamps and go to the next block. If you don't use screws, you'll have to wait for the glue to setup before you can move to the next block.