I have tried in another computer, also with Windows 10. This computer's screen is 1920x1080. I have made a layout at a fixed size of 1280x720. When I run it using ChangeResolution=1 again all games run at around 80%. Actually, when I quit MaLa and the resolution of 1920x1080 is restored, the mouse pointer, the windows, everything moves slowly and stutters. I have to change the resolution from Windows control panel to go back to a normal performance. This is very weird. Anyway, a workaround in case I need to scale a layout to a higher resolution is to always set ChangeResolution=0 and automate the resolution change with nircmd before MaLa starts and restore it on exit.