So I wanted to update my post, in case it helps anyone down the road. I have a basic working system, with all the subcomponents integrated and working as intended. I'm still in the process of "beautifying" the cabinet (painting, decals, few cosmetic improvements, etc.). However, the core functionality is now there, and IMO, that was the hardest part. Hopefully this can help someone else down the road if they want to create a dual-use retro-arcade system (Mister FPMA + MAME style PC):
Gaming systems:
PC Running BigBox/Launchbox, using RetroArch and MAME as main emulators
Mister FPGA
Displays:
JVC I'art 27" CRT with component Input
LCD Monitor (for now, for configuring. Will eventually replace with a Marquee-style LCD, such
https://pixelcade.org/lcd/)
Audio:
Specialized Hardware:
KVM: CKL HDMI + VGA Dual Monitor KVM (Specifically chosen because it has external switch which can be modified to allow externalizing controls to front of arcade cabinet)
https://www.amazon.com/gp/product/B07YZ6RPTV/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&th=1Sapphire Nitro R9 380x GPU (highest-end AMD GPU that can still output analog 15khz signal via Emudriver, and as a ROM that can be flashed with Atom-15, which will force 15khz signal during Windows boot-up).
VGA to Component transcoder. There are several options, but currently I'm running a
https://www.ebay.com/itm/174166352619, which is made by a well-known arcade enthusiast (I believe he's on this board).
Audio:
DAC (digital to analog converter, to take Toslink audio from Mister FPGA and convert it to Analog to feed speakers. The native Analog out from Mister FPGA is pretty poor quality)
Logitech Z333 Speakers and subwoofer (specifically chosen b/c they have an external control unit, which can be modified to externalize audio controls for arcade cabinet)
Controls:
USB Hub (had to try a few until I fond one that worked with Mister FPGA and KVM switching)
https://www.amazon.com/gp/product/B075NMVGP7/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1Ultimarc Ultimate I/O
https://www.ultimarc.com/control-interfaces/i-pacs/i-pac-ultimate-i-o/Ultimarc Servostik x 2
https://www.ultimarc.com/arcade-controls/joysticks/servostik/Servostik controller board x 1 (can control two Servostiks)
https://www.ultimarc.com/arcade-controls/joysticks/servostik-control-board/Various RGB buttons, harness extension and RGB extension wires from Ultimarc
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The Setup:
The KVM feeds pre-processed video signal to the CRT, via a VGA to Component (RCA) breakout cable:
https://www.amazon.com/gp/product/B001T6OHNU/ref=ppx_yo_dt_b_search_asin_title?ie=UTF8&psc=1Mister:
Analog output (VGA socket) ==> KVM "PC 2" VGA input
HDMI output ==>KVM "PC 2" HDMI Input
USB hub of Mister ==> KVM "PC2 USB"
Toslink Audio out ==> DAC ==> KVM "PC 2 Audio In"
PC Running BigBox/LaunchBox:
DVI-I (On Sapphire GPU running EmuDriver) --> DIV-I to VGA adapter --> VGA to Component Transcoder --> Component to VGA break-out cable (same cable as above, just in reverse order) --> KVM "PC1" VGA Input
HDMI Out --> KVM "PC1" HDMI Input
Line out --> KVM "PC1" Audio In
KVM:
Powered USB Hub -->Front USB port (all shared USB peripherals, such as I-PAC controller, etc. plug into the hub)
Audio, VGA and HDMI Inputs from the two systems (see above)
VGA Out --> VGA to Component break-out cable --> CRT
HDMI Out --> Marquee (or spare monitor for configuring)
Audio Out --> Logitech Subwoofer, which controls L and R speakers and has external audio control switch. Speakers are mounted in the cabinet, behind the Marquee.
I also spent a fair bit of time learning basic electronics/soldering, and had to purchase related equipment (Soldering and de-soldering station + a dedicated soldering iron), to externalize the KVM control and audio control, to a 3D printed control panel on the front of the arcade. This is definitely optional, but makes for a cleaner look (but took ... months to work out, design, etc.).
I'm still in the process of "beautifying" the cabinet (has no paint, artwork, etc.). Once it's all done, I hope to update this post and add pictures.