It's true, a vertical game on horizontal monitor isn't the best option...
In my case, for these games than transposed vertical lines exceed 240 narrowly (256 or 288), i prefer configure it for 240 with pixel perfect.
For example por pacman machine.
In /ini/source create pacman.ini file with
resolution 2560x240
unevenstretch 0
You can adjust vertical position with slider if you prefer top/bottom lines depending on the game.
(*) I'm sure it's possible do the same playing with crt_range but it's more friendly for me this method.