Fantastic condition on that Defender!
When you power-up, does it go into the game after the test patterns, or to the setup menu? If it always goes to the set-up menu, you have a CMOS problem, which could contribute to the high score saving.
Also, is it running on the original Linear PSU? Or a newer switcher? I've read that switching PSU's have a different timing pattern that messes with the 5101 CMOS memory.
Is the board still on the 3x AA batteries? If so, I would highly recommend converting it to the
Lithium Battery upgrade.
There's also a
NVRAM upgrade, eliminating the need for battery backup at all. But I've been sceptical of these NVRAM replacements, as I have one similar on a Gyruss board, and it's power hungry so I had to either run the board at a higher voltage to get it to work, or tap a 5v line from the jamma edge and power the NVRAM before the 5v gets too much load.
Lets see some pictures of the boards, and PSU.