I think it's an interesting idea. I have a cut down panel in one of my machines and I love it but it did cost mucho mucho when I got it.
If you're cutting down a screen anyway then you could do a square 1:1 monitor, and then you'd hit the sweet spot of running vertical and horizontal without having to rotate the screen. That would be pretty cool.
Assuming you could get decent screens, ie good blacks, high resolution (for filters) and low latency then it could be great. But - I just don't see that combination being cheap - but good luck