The feature that's required is pixel aspect ratio correction, and as far as I know the Windows desktop does not support this.
The supported scaling methods are designed to compensate for mismatches in the resolution aspect ratio, e.g. to accommodate a 4:3 resolution in a 16:9 monitor, always assuming that in both cases those resolutions in their native aspect ratio have square pixels (pixel aspect ratio = 1).
The issue here is different, because super resolutions mean extreme pixel aspect ratios (<<<1). In order to compensate for this, for instance, the OS would need to use font sizes that are much much wider than tall. This is what Arcade OSD does. Besides all icons, window borders, etc. would need to be scaled unevenly.
If anyone is aware of a way to achive this, please let us know.