Sky is the limit. You can use 2.1 speaker set or a arcade amp with 2 channels on 4 channels where you can (i suppose) put the 2 channels in cross for bass.
I myself use a arcade 2 channel and 6.5” 60w car speakers on my project(4Ohm) but any speakers will do.
All depends on how much you want to put time, effort and money for it.
Im think going to install my amp inside the kb/mouse drawer, because making it visible could be complicated.