As calamity just posted in the thread I started about cloning, you should use a 5000/6000/7000 series card for preference. The EDID emulation works more smoothly, the cards are the same vintage as Win7 which is the preferred platform for crt_emudriver, and you won't get any hiccups with the resolution accidentally reverting.
Note that the 6000 and 7000 series cards, while more powerful, only have one DVI-I port. You can only run one analog monitor from them.
And, and this is something I think we need to figure out properly, the picture quality seems to improve as you get newer, higher end cards. The 4350's look washed out, and they flicker badly at 480i. I upgraded to a 6870 just the other day, and the colours are much more vivid, and the displays I'm driving flicker a lot less. My 4890 is almost as nice. I've heard someone report that changing to a 5450 is a step up from the 4350, as well, in terms of there being much less flicker.
I'm not sure if this phenomenon is a cut-off (as in, all of a sudden they upgraded the RAMDAC or line drivers or something, once you get to a certain point) or a series of steps, or a sliding scale, or even something else.