Hi repetto74,
First of all, sorry for merging your topics but I thought they made more sense together as they're both about GM running interlaced modes, which by the way is not a particular game issue but actually a feature
Interlaced modes are used as a way to provide the best possible resolution for your monitor, when a native progressive resolution is not a possibility due to your monitor specs. This allows for the best possible detail, at the cost of some flicker, let's say it's the less bad solution if you can't physically rotate your monitor (in case of vertical games which often lead to this problem on standard monitors).
The problem is, some monitors just suck when it comes to displaying interlaced modes. Sometimes it's the graphic card.
For these cases you can just disable the -interlace option in mame.ini. This will force GM to always pick progressive modes. See how these games look when stretched over a progressive resolution and decide which method looks better for your particular monitor.